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10.1016/S0140-6736(14)61909-7 16 BovenschenH

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Heme oxygenase-1 (HO-1) is an important source of intracellular iron that accelerates erastin-mediated ferroptotic cell death by provision of iron (Kwon et al., 2015)

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While studies have identified key regulators of GPX4-restricted LPO and cellular demise 1,2,6,12,13,14 , mechanism(s) of concurrent inflammatory responses remain elusive